Pamaryl

Pamaryl 2mg Tablets

Product Overview:

Pamaryl 2mg tablets are an oral hypoglycemic medication used to help manage blood sugar levels in adults with type 2 diabetes. Manufactured by Sanofi Aventis, these tablets contain the active ingredient glimepiride, which belongs to the sulfonylurea class of drugs.

Key Information:

• Form and Strength: Each tablet contains 2 milligrams of glimepiride.
• Packaging: Available in packs of 20 tablets.
• Indication: Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.
• Ingredients: Glimepiride, lactose (hydrous), sodium starch glycolate, povidone, microcrystalline cellulose, and magnesium stearate. The 2mg tablets also contain Ferric Oxide Yellow and FD&C Blue #2 Aluminum Lake.
• Administration: Taken orally, once daily, with or without food.
• Absorption: Glimepiride is completely absorbed from the gastrointestinal tract, with peak levels typically reached within 2 to 3 hours after administration.

Clinical Use:

Pamaryl 2mg tablets have been shown to improve postprandial insulin/C-peptide responses and overall glycemic control in clinical trials. In long-term studies, 75% of patients achieved and maintained control of blood glucose and HbA1c levels. The medication is effective in controlling blood glucose without causing significant changes in plasma lipoprotein profiles.

Important Notes:

• Dosage: The recommended dose can vary depending on individual patient needs, but typically ranges from 1 to 8 milligrams per day.
• Interactions: There is a potential interaction with inhibitors and inducers of cytochrome P450 2C9, such as fluconazole and rifampicin. However, no clinically significant adverse interactions have been reported with other commonly used medications like ACE inhibitors, calcium-channel blockers, estrogens, fibrates, NSAIDs, HMG CoA reductase inhibitors, sulfonamides, or thyroid hormone.

By following this regimen and maintaining a healthy lifestyle, individuals with type 2 diabetes can effectively manage their blood sugar levels and improve their overall health.