Colitran

Colistimethate for Injection: Effective Treatment for Gram-Negative Infections

Colistimethate for Injection is a powerful antibiotic used to treat acute or chronic infections caused by sensitive strains of certain gram-negative bacilli. It is particularly effective against Pseudomonas aeruginosa, a common pathogen in hospitals. This medication is also indicated for infections caused by Enterobacter aerogenes, Escherichia coli, and Klebsiella pneumoniae.

Colistimethate is administered intravenously or intramuscularly and should be reconstituted with sterile water for injection. The recommended dosage is 2.5 to 5 mg/kg of colistin base activity per day, divided into 2 to 4 doses, depending on the severity of the infection. For patients with renal impairment, the dosage should be adjusted according to the degree of impairment.

This medication is supplied in vials containing 150 mg of colistin base activity and is available for immediate use. It is essential to follow the reconstitution instructions carefully to ensure the solution is free from particulate matter and discoloration.

Colistimethate is a crucial treatment option for serious infections caused by gram-negative bacteria, especially when other antibiotics are ineffective. It should be used under the guidance of a healthcare professional to ensure the best possible outcome.