Amplus 500mg

Amplus 500mg Injection: Effective Treatment for Bacterial Infections

Amplus 500mg is a powerful antibiotic injection designed to combat a wide range of bacterial infections. This combination of ampicillin and cloxacillin works by interfering with the formation of new bacterial cell walls, effectively killing the microorganisms that cause infections.

Therapeutic Indications:

• Respiratory Infections: Amplus is effective in treating bronchopneumonia and acute exacerbations of chronic bronchitis.
• Surgery: It helps prevent and treat post-operative wound infections and pulmonary infections.
• Obstetrics: It is used to treat puerperal fever.
• Other Infections: Amplus is also indicated for septicaemia, bone infections like osteomyelitis, and ear, nose, and throat infections.

Dosage and Administration:

• Adults and Elderly: The recommended dose is 500 mg to 1 g every 4 to 6 hours, either intramuscularly or intravenously.
• Children 2 to 12 Years: Half the adult dose is administered every 6 hours orally or every 8 hours intramuscularly.
• Neonates to 2 Years: The neonatal suspension is given 0.6 ml (90 mg) every 4 hours, while the injection is administered 75 mg every 8 hours.

Important Considerations:

• Creatinine Clearance Below 10 ml/minute: The dose should be reduced and administered twice or once daily.
• Hepatic Impairment: The frequency of administration should be adjusted based on the severity of the condition.
• Dialysis: An additional dose should be given after the procedure.

Stability and Compatibility:

• Amplus is stable with commonly used intravenous fluids at 23°C if infused over 6 hours..
• Solutions containing dextrose or other carbohydrates should be changed after 2 hours, while those with sodium bicarbonate should be changed within 4 hours..

Storage:

• The injection should be stored in a cool, dry place below 25°C..
• Once dispensed, the syrup should be used within 7 days..

Availability:

Amplus is available in various forms, including capsules and injections, ensuring it can be administered according to the patient’s needs..

This comprehensive overview ensures that readers have all the necessary information to understand the effectiveness and proper use of Amplus 500mg injection.