Cara-Doba 250mg Inj

Cara-Doba 250mg Injection: A Comprehensive Overview

Cara-Doba 250mg Injection is a medication designed to provide inotropic support in the short-term treatment of adults with cardiac decompensation due to depressed contractility resulting from organic heart disease or cardiac surgical procedures. This injection is indicated for use when parenteral therapy is necessary, helping to increase cardiac output and improve heart function.

Key Features:

• Indication: Short-term treatment of cardiac decompensation in adults.
• Administration: Must be further diluted in an intravenous container with one of several recommended solutions, such as 5% Dextrose Injection or Lactated Ringer’s Injection, before administration.
• Dosage: The rate of infusion typically ranges from 2.5 to 15 mcg/kg/min, with some cases requiring up to 40 mcg/kg/min for optimal effect.
• Contraindications: Not recommended for patients with idiopathic hypertrophic subaortic stenosis or those who have shown hypersensitivity to the solution.
• Side Effects: Common adverse effects include nausea, headache, anginal pain, nonspecific chest pain, palpitations, and shortness of breath. Rarely, it can cause thrombocytopenia and hypokalemia.

Important Considerations:

• Precautions: Avoid mixing with 5% Sodium Bicarbonate Injection or other strongly alkaline solutions. Do not use with agents containing both sodium bisulfite and ethanol.
• Monitoring: The rate of administration and duration of therapy should be adjusted according to the patient’s response, monitored by heart rate, blood pressure, urine flow, and central venous or pulmonary wedge pressure.

Cara-Doba 250mg Injection is a clear, practically colorless, sterile solution of dobutamine hydrochloride for intravenous use only. Each milliliter contains 12.5 mg of dobutamine as the hydrochloride and sodium metabisulfite as an antioxidant. This medication is a direct-acting inotropic agent that stimulates ? receptors of the heart while producing mild chronotropic, hypertensive, arrhythmogenic, and vasodilative effects. It is essential to inspect the solution visually for particulate matter and discoloration before administration.