Dopilax

Dovonex Calcipotriol Cream and Ointment for Psoriasis Treatment

Dovonex calcipotriol cream and ointment are topical treatments specifically designed to help manage psoriasis vulgaris, also known as plaque psoriasis. This medication works by regulating cell proliferation and differentiation, which helps to normalize the growth of keratinocytes, the skin cells affected by psoriasis.

The cream and ointment contain 50 mcg of calcipotriol per gram, a non-steroidal antipsoriatic agent derived from vitamin D. Calcipotriol competes with the naturally occurring active form of vitamin D, 1,25(OH)2D3, for receptor sites, thereby inducing differentiation and suppressing proliferation of keratinocytes without causing cytotoxic effects.

Clinical trials have shown that Dovonex cream and ointment are highly effective in treating psoriasis. Patients typically experience significant improvements within two weeks of treatment, with symptoms such as thickness, erythema, and scaling significantly reduced. The efficacy of Dovonex ointment and cream is similar, with the best results achieved after 6 to 8 weeks of treatment.

Dovonex can also be used in combination with topical corticosteroids for enhanced efficacy. This combination therapy allows for once-daily steroid administration or reduced doses of systemic drugs like cyclosporin A or acitretin, thereby minimizing potential adverse effects associated with these agents.

For optimal use, it is recommended to monitor serum calcium levels weekly until they return to normal. Dovonex is for external use only and should be applied carefully to avoid contact with the face or eyes.

Overall, Dovonex calcipotriol cream and ointment offer a reliable and effective solution for managing psoriasis, providing rapid clinical improvement and long-term control of the condition.