Matacin

Macitentan (Opsumit) for Pulmonary Arterial Hypertension

Macitentan, also known as Opsumit, is a medication used to manage the symptoms of pulmonary arterial hypertension (PAH). PAH is a condition where the blood vessels in the lungs become narrowed, leading to high blood pressure in these vessels. This condition forces the right side of the heart to work harder to pump blood through the lungs, which can lead to heart failure if left untreated.

Macitentan works by blocking the action of endothelin, a natural substance that causes blood vessels to narrow. By preventing this narrowing, macitentan helps to relax the blood vessels in the lungs, increasing blood flow and reducing the workload on the heart.

This medication is available in a 10 mg film-coated tablet, which is taken orally once a day. It is usually taken with or without food and should be swallowed whole, not split, chewed, or crushed.

Macitentan is particularly beneficial for patients with PAH, as it has been shown to improve quality of life and reduce symptoms. It is also effective in reducing pulmonary vascular resistance, a key indicator of PAH severity. The medication has been proven to improve functional class in patients with PAH, allowing them to perform daily activities more easily.

If you have been prescribed macitentan, it is essential to follow your doctor’s instructions carefully and take the medication exactly as directed. If you have any questions or concerns about macitentan, consult with your healthcare provider for more information.