Calypsol 500mg

Calypsol 500mg Injection: A General Anesthetic for Major Surgical Procedures.

Calypsol 500mg injection is a powerful general anesthetic used in major surgical procedures. It helps patients remain pain-free and calm during operations, allowing medical professionals to perform complex surgeries without distress. This medication is administered under the close supervision of a healthcare professional in a hospital setting.

Uses of Calypsol

General Anesthesia: Calypsol induces a reversible loss of consciousness, making it ideal for surgeries that require patients to be fully anesthetized.

Side Effects

Common side effects include:

• Rash.
• Erythema (skin redness).
• Vomiting.
• Nausea.
• Agitation.
• Nightmare.
• Abnormal behavior.
• Double vision.
• Hallucination.
• Increased respiratory rate.
• High blood pressure.
• Confusion.
• Nystagmus (involuntary eye movement).
• Muscle coordination impaired.
• Tonic-clonic seizures.
• Tachycardia.

Precautions and Contraindications

• Liver Disease: Dose adjustment may be necessary for patients with liver disease.
• Hypertension, Cerebrovascular Accident, Eye Injury, Raised Ocular and Intracranial Pressure: Avoid using Calypsol in patients with these conditions.
• Psychotic Disorders: Use with caution in patients with a history of psychotic disorders.
• Pregnancy and Breastfeeding: Consult your doctor before taking Calypsol if you are pregnant or breastfeeding.
• Driving and Alcohol Consumption: Avoid driving and consuming alcohol while using this medication.

Administration

Calypsol is available in 50 mg/mL and 100 mg/mL vials. It can be further diluted in 5% dextrose or 0.9% NaCl to prepare a maintenance infusion containing 1 mg/mL or 2 mg/mL for patients with fluid restrictions.

Dosage

• Intravenous Induction: Adults: 1-4.5 mg/kg via slow IV injection over 60 seconds. A dose of 2 mg/kg produces surgical anesthesia within 30 seconds, lasting 5-10 minutes. Increments of half to the full induction dose may be repeated as needed for maintenance of anesthesia.
• Intramuscular Induction: Adults: 6.5-13 mg/kg. A dose of 10 mg/kg produces surgical anesthesia within 3-4 minutes, lasting 12-25 minutes.

How It Works

Calypsol works by causing a reversible loss of consciousness, allowing surgical procedures to be carried out without pain and distress. It is a noncompetitive N-methyl-D-aspartate receptor antagonist that blocks glutamate, producing a cataleptic-like state where the patient is withdrawn from the surrounding environment.