Depo-Medrol

Depo-Medrol: A Comprehensive Overview

Depo-Medrol is an anti-inflammatory glucocorticoid designed for intramuscular, intra-articular, soft tissue, or intralesional injections. It is available in two strengths: 40 mg/mL and 80 mg/mL. Each milliliter of the preparation contains:

• Methylprednisolone Acetate: 40 mg or 80 mg.
• Polyethylene Glycol 3350: 29 mg or 28 mg.
• Myristyl-gamma-picolinium Chloride: 0.195 mg or 0.189 mg.

Sodium Chloride is added to adjust tonicity, and the pH is adjusted with sodium hydroxide and/or hydrochloric acid to ensure it remains within the USP specified range (3.0 to 7.0).

Indications and Uses

Depo-Medrol is indicated as adjunctive therapy for short-term administration to manage acute episodes or exacerbations in various conditions, including:

• Acute Gouty Arthritis.
• Acute and Subacute Bursitis.
• Acute Nonspecific Tenosynovitis.
• Epicondylitis.
• Rheumatoid Arthritis.
• Synovitis of Osteoarthritis.

It is also used for intralesional administration in conditions such as alopecia areata.

Important Notes

• Not for Intravenous Use: Depo-Medrol is not intended for intravenous administration.
• Consult a Healthcare Professional: Always consult a healthcare professional before using Depo-Medrol, especially if you have any underlying medical conditions or are taking other medications.

By understanding the composition and uses of Depo-Medrol, you can make informed decisions about its application in your medical treatment plan.