Diklonat P

Diclofenac Sodium Delayed-Release Tablets

Diclofenac Sodium Delayed-Release Tablets are a type of nonsteroidal anti-inflammatory drug (NSAID) designed to provide relief from pain, inflammation, and fever. These tablets contain 25 mg, 50 mg, or 75 mg of diclofenac sodium, a benzeneacetic acid derivative.

Mechanism of Action

Diclofenac works by inhibiting the production of prostaglandins, which are mediators of inflammation. This action helps reduce pain and inflammation in the body. The exact mechanism is not fully understood, but it involves the inhibition of cyclooxygenase (COX-1 and COX-2) enzymes, which are crucial for prostaglandin synthesis.

Indications and Usage

Diclofenac Sodium Delayed-Release Tablets are indicated for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. They are designed for oral administration and are available in enteric-coated tablets to minimize gastrointestinal side effects.

Key Ingredients

Each tablet contains the active ingredient diclofenac sodium along with inactive ingredients such as lactose (monohydrate), microcrystalline cellulose, croscarmellose sodium, povidone, talc, magnesium stearate, methacrylic acid copolymer, polyethylene glycol, opadry brown (Titanium dioxide, hypromellose, polyethylene glycol, iron oxide red, iron oxide yellow), and purified water.

Clinical Use

When using Diclofenac Sodium Delayed-Release Tablets, it is essential to use the lowest effective dose for the shortest duration necessary to achieve the desired therapeutic effect. This approach helps minimize the risk of gastrointestinal bleeding, ulceration, and perforation.

Diclofenac Sodium Delayed-Release Tablets are a reliable option for managing chronic pain and inflammation associated with various arthritic conditions. They offer a convenient and effective way to alleviate symptoms and improve quality of life for those suffering from these conditions.