Loxicam

Meloxicam: Relieving Arthritis Pain with Ease

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) designed to alleviate the pain and swelling associated with various types of arthritis, including osteoarthritis and rheumatoid arthritis. It is also used to treat juvenile rheumatoid arthritis in children aged 2 years and above. This medication works by inhibiting prostaglandin synthetase enzymes, which are responsible for producing prostaglandins that cause pain and inflammation.

Key Features

• Long-Lasting Relief: Meloxicam has a longer half-life compared to other NSAIDs, making it suitable for once-daily dosing.
• Gastrointestinal Protection: As a preferential COX-2 inhibitor, meloxicam is thought to cause less gastrointestinal irritation, though it still carries a risk of gastric inflammation, bleeding, and ulceration.
• Versatile Formulations: Available in oral, transdermal, and intravenous forms, making it adaptable to different medical needs.
• Effective for Various Conditions: Indicated for the symptomatic treatment of arthritis and osteoarthritis, as well as for off-label uses such as dental or post-surgical pain.

How It Works

Meloxicam inhibits the synthesis of prostaglandins, which are mediators of painful inflammatory symptoms. By preferentially inhibiting COX-2, it reduces the risk of gastrointestinal irritation, although some activity against COX-1 can still occur, leading to potential gastrointestinal side effects.

Important Information

• Common Brand Names: Anjeso, Mobic, Qmiiz, Vivlodex, Zynrelef.
• Generic Name: Meloxicam.
• Clinical Use: Symptomatic treatment of arthritis and osteoarthritis; treatment of juvenile rheumatoid arthritis in children aged 2 years and above; off-label uses for dental or post-surgical pain.

By understanding how meloxicam works and its various formulations, you can make informed decisions about your treatment options. Always consult with your healthcare provider before starting any new medication.