Piroxibin

Piroxicam: Effective Relief for Painful Inflammatory Conditions

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the symptoms of painful inflammatory conditions like rheumatoid and osteoarthritis. It works by preventing the production of endogenous prostaglandins, which are involved in the mediation of pain, stiffness, tenderness, and swelling.

Available in various forms, including capsules and tablets, piroxicam is also available in a betadex formulation that allows for more rapid absorption from the digestive tract. This medication is particularly useful for treating chronic inflammatory conditions, as it offers a favorable risk-benefit ratio in these cases.

Piroxicam is commonly used to treat conditions such as rheumatoid arthritis and osteoarthritis, providing significant relief from pain and inflammation. It is also effective in managing primary dysmenorrhoea and postoperative pain. However, it is essential to note that the U.S. Food and Drug Administration recommends avoiding NSAIDs in pregnant women at 20 weeks or later in pregnancy due to the risk of kidney problems in unborn babies.

Piroxicam is available under various brand names, including Feldene, and has been widely used since its approval in 1979. It is essential to store piroxicam at room temperature, between 68°F to 77°F (20°C to 25°C), to maintain its effectiveness.

By blocking certain substances in the body that cause pain, inflammation, and fever, piroxicam provides effective relief for those suffering from painful inflammatory conditions. Its long-lasting effects, with an elimination half-life of 50 hours, make it a reliable choice for managing chronic pain and inflammation.