Tienam

Tienam: A Broad-Spectrum Antibiotic for Effective Infection Treatment

Tienam is a powerful, broad-spectrum antibiotic designed to combat a wide range of bacterial infections. This medication is a combination of imipenem and cilastatin sodium, which work together to provide potent bactericidal activity against both gram-positive and gram-negative bacteria, including anaerobic pathogens.

Key Features:

• Broad Spectrum Activity: Tienam is effective against a broad spectrum of pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, and Bacteroides fragilis.
• Unique Mechanism: The thienamycin class of antibiotics, to which imipenem belongs, is resistant to degradation by bacterial beta-lactamases, making it active against many organisms that are inherently resistant to other beta-lactam antibiotics.
• Intravenous Administration: Tienam is supplied as a sterile powder for intravenous infusion, ensuring high concentrations of the antibiotic in the bloodstream and urinary tract.
• Indications: This antibiotic is indicated for the treatment of various infections, including intra-abdominal infections, lower respiratory tract infections, gynecological infections, septicemia, genitourinary tract infections, bone and joint infections, skin and soft tissue infections, and endocarditis.
• Dosage: The maximum total daily dosage should not exceed 50 mg/kg/day or 4 g/day, whichever is lower. However, cystic fibrosis patients with normal renal function may be treated with higher doses up to 90 mg/kg/day in divided doses, not exceeding 4 g/day.

Why Choose Tienam?

Tienam is a reliable choice for treating complex infections due to its broad-spectrum activity and unique mechanism of action. Its effectiveness in combating a wide range of pathogens makes it particularly useful in polymicrobic and mixed aerobic/anaerobic infections. Whether you’re treating a severe infection or need initial therapy before identifying the causative organisms, Tienam is a trusted option.