Xynap

XYNTHA: Effective Treatment for Hemophilia A

XYNTHA is a recombinant antihemophilic factor designed to treat bleeding episodes in adults and children with hemophilia A. It is used for on-demand treatment, perioperative management, and routine prophylaxis to reduce the frequency of bleeding episodes. This medication is not indicated for patients with von Willebrand’s disease.

Key Features:

• Indication: XYNTHA is specifically formulated for individuals with hemophilia A to manage and prevent bleeding episodes.
• Administration: It is administered intravenously after reconstitution with a provided diluent.
• Dosage: The required dose is calculated based on body weight and desired factor VIII rise, ensuring effective treatment.
• Preparation: The product comes in various dosages (250, 500, 1000, and 2000 IU) and is available in both vial and prefilled dual-chamber syringe formats.
• Safety: The purification process includes steps like affinity chromatography and solvent-detergent viral inactivation to ensure safety and efficacy.

Usage Instructions:

1. **Reconstitution:** Reconstitute the lyophilized powder with the provided diluent by slowly depressing the plunger rod into the vial.

2. **Inspection:** Visually inspect the solution for particulate matter before administration. The final solution should be clear to slightly opalescent and colorless.

3. **Administration:** Invert the vial and slowly draw the solution into a syringe. Detach the syringe from the vial adapter and discard the empty vial.

Storage and Handling:

• Store the reconstituted solution at room temperature..
• Use the solution within 3 hours after reconstitution..
• Avoid touching the rubber stopper or allowing it to touch any surface during preparation..

**Manufacturer:** Wyeth Pharmaceuticals, LLC, a subsidiary of Pfizer.

By using XYNTHA, individuals with hemophilia A can effectively manage their condition and reduce the frequency of bleeding episodes. This medication is a reliable choice for those seeking a safe and effective treatment option.