Amodiaquine 150mg: Effective Antimalarial Treatment
Amodiaquine 150mg is a powerful antimalarial medication used to treat uncomplicated malaria caused by Plasmodium species, including Plasmodium falciparum. It is often prescribed in combination with artesunate, especially when chloroquine cannot be used. This medication is effective against some chloroquine-resistant strains of malaria, making it a reliable option for treating various types of malaria.
Key Information
- Indications: Treatment of uncomplicated malaria due to Plasmodium species, including P. falciparum, P. vivax, P. ovale, P. knowlesi, and P. malariae.
- Dosage: Typically administered orally at a dose of 25-35 mg/kg over 3 days, or in partially immune subjects, a single dose of 600 mg.
- Forms: Available as tablets containing 150 mg of amodiaquine base.
- Contraindications: Not recommended for patients with severe liver impairment, hypersensitivity to 4-aminoquinoline derivatives, or those taking efavirenz.
- Side Effects: May cause gastrointestinal disturbances, pruritus, cough, insomnia, and in rare cases, more severe reactions like hepatitis or leucopenia.
Important Precautions
- Liver Function: Use with caution in patients with hepatic disease or alcoholism.
- Allergies: Avoid in patients with known hypersensitivity to 4-aminoquinoline derivatives.
- Pregnancy and Breastfeeding: Generally safe but consult a healthcare provider for personalized advice.
Amodiaquine 150mg is a crucial medication for managing malaria, especially when used in combination with other antimalarial agents. Always consult a healthcare provider for the most accurate dosing and usage instructions.
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