Medroxyprogesterone (Provera) is a hormone medication used to treat conditions such as absent or irregular menstrual periods, abnormal uterine bleeding, and to prevent the thickening of the uterine lining in postmenopausal women taking estrogen hormone replacement therapy. It is a progestin hormone that helps regulate the menstrual cycle and prevent endometrial hyperplasia.
Uses
- Treatment of Secondary Amenorrhea: Medroxyprogesterone is prescribed to treat irregular menstrual periods due to hormonal imbalance, excluding conditions like fibroids or uterine cancer.
- Abnormal Uterine Bleeding: It helps manage abnormal bleeding caused by hormonal imbalances.
- Prevention of Endometrial Hyperplasia: In postmenopausal women taking estrogen, medroxyprogesterone prevents the thickening of the uterine lining, which can reduce the risk of endometrial cancer.
Dosage
- The typical dosage for inducing an optimal secretory transformation of the endometrium is 10 mg daily for 10 days..
- Therapy can be started at any time, and withdrawal bleeding usually occurs within 3 to 7 days after discontinuing the medication..
Important Information
- Missed Dose: If you miss a dose, take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
- Overdose: Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if you suspect an overdose.
- Precautions: Avoid smoking while taking medroxyprogesterone, as it increases the risk of blood clots.
Medroxyprogesterone is available under the brand names Provera, DepoProvera, and Depo-SubQ Provera 104. Always consult with your healthcare provider for proper guidance on using this medication.
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