Loricin

Loricrin Antibody for Research.

The Loricrin Antibody (55439-1-AP) is a polyclonal antibody designed for various research applications, including Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), and ELISA. This antibody targets Loricrin, a major component of the cornified cell envelope in the skin, and shows reactivity with human, mouse, and rat samples.

Key Features

• Host and Isotype: Rabbit IgG.
• Reactivity: Human, Mouse, Rat.
• Applications: WB, IHC, IF, ELISA.
• Conjugate: Unconjugated.
• Recommended Dilution:
• WB: 1:500-1:3000.
• IHC: 1:200-1:800.

Product Information

This antibody is ideal for researchers studying epidermal differentiation and skin barrier formation. It has been tested in various applications and shows strong reactivity with Loricrin in different species. The antibody is available in a liquid form and is purified using antigen affinity purification methods. It is stored in PBS with 0.02% sodium azide and 50% glycerol at -20°C.

Background Information

Loricrin is a crucial protein in the formation of the cornified cell envelope, which provides a strong barrier against environmental factors. Mutations in the LORICRIN gene can lead to skin disorders such as Vohwinkel syndrome, characterized by dry, scaly skin.

Protocols

• WB Protocol: Download the detailed protocol for Western Blot analysis.
• IHC Protocol: Download the detailed protocol for Immunohistochemistry analysis.

This antibody is a valuable tool for researchers studying skin biology and related disorders. Its high specificity and broad reactivity make it suitable for a variety of experimental setups.